Webinars provided here present a range of approaches for modeling different biological and ecological systems – spanning from cells and individuals to populations.
View all of our workshop presentations at the g2p2pop Youtube Channel
Jason Podrabsky (Portland State University) – “Epigenetic regulation of development, dormancy, and stress tolerance in a vertebrate extremophile”
Irene Kaplow (Carnegie Mellon) – “Relating enhancer genetic variation across mammals to complex phenotypes using machine learning”
Mira Han (UNLV) – “Learning the effect of 3D genome organization on gene expression”
Kathleen Keough (Fauna Bio) – “Genome evolution over multiple timescales and dimensions”
Daniel Neafsey (Broad Institute) – “Longitudinal population genomics to explore life history adaptation in malaria parasites”
Kathleen Morrill (Broad Institute) – “Low-pass sequencing + imputation: a cost-effective strategy for genotyping”
Lauren Wasson (Harvard Medical) – “Integration of RNA-seq and chromatin accessibility for genome-wide expression analysis”
Athma Pai (UMass Chan Medical) – “RNA as a dynamic molecule: how and when our cells regulate mRNA splicing”
Rachel Johnston (Broad Institute) – “The genomic and phenotypic consequences of breeding status in social mole-rats”
John DeLong (University of Nebraska Lincoln) – “Climate change and scaling up across levels with evolution”
Jonathan Karr (Icahn School of Medicine at Mount Sinai) – “Whole-Cell Modeling: Predicting Phenotype from Genotype for Science, Medicine & Engineering – Toward WC models for predicting cellular phenotypes”
Valery Forbes (University of Minnesota) – “Extrapolating across levels of biological organization and how mechanistic models can help”
Roger Nisbet (University of California – Santa Barbara) presented the basics of the Dynamic Energy Budget theory which provides a coherent framework for linking information across levels of biological organization. For those who would like to dive deeper into the theory than what is provided in this introductory webinar, Prof. Nisbet suggests to have a look at this series of webinars: http://www.cein.ucla.edu/new/p156.php?pageID=367
Valery Forbes (University of Minnesota – Twin Cities) presented why we need ecological models to translate what we measure in the lab to what we aim to protect in the field. For instance, impacts measured on individual organisms need to be translated to consequences on population properties and ecosystem services, as these are typically of interest for long-term conservation. This webinar has been recorded at a workshop at the National Institute for Mathematical and Biological Synthesis (NIMBioS).
Volker Grimm (Helmholtz Centre for Environmental Research – UFZ; University of Potsdam) presented on a modeling approach that links individuals to properties at higher levels of biological organization. Individual-based modeling allows for combining all relevant life-history information with impacts of stressors and through a simulation-based approach translates stressor effects on populations and communities. This webinar has been recorded at a workshop at the National Institute for Mathematical and Biological Synthesis (NIMBioS).
Irvin Schultz (Lynker Technologies, Northwest Fisheries Science Center, National Marine Fisheries Service, NOAA) presented on models that can link molecular interactions to organismal properties. Pharmacokinetic and pharmacodynamic modeling approaches allow for translating cascading effects of endocrine disrupting chemicals in, for instance, the brain-pituitary-gonad-liver axis in fish. This webinar has been recorded at a workshop at the National Institute for Mathematical and Biological Synthesis (NIMBioS).
Jonathan Karr (Icahn School of Medicine at Mount Sinai) presented the development of a whole-cell model and its possible applications for biomedical science and engineering. This talk has been recorded at the 2014 Japan-American Frontiers of Science Symposium.