{"id":301,"date":"2023-04-24T22:20:40","date_gmt":"2023-04-24T22:20:40","guid":{"rendered":"https:\/\/nau.edu\/research\/?page_id=301"},"modified":"2024-12-12T17:31:50","modified_gmt":"2024-12-12T17:31:50","slug":"infections","status":"publish","type":"page","link":"https:\/\/in.nau.edu\/research\/innovations\/available-technologies\/biomedical\/infections\/","title":{"rendered":"Systems and Methods of Diagnosing and Characterizing Infections"},"content":{"rendered":"<div class=\"nau-block nau-block-left-nav-top-bound\">\n    \t<button id=\"left-nav-toggle-btn\" onclick=\"toggleNav();\">\n\t\tON THIS PAGE \n\t\t<i id=\"chevron-icon\" class=\"fas fa-solid fa-chevron-down\"><\/i>\n\t<\/button>\n\t<div id=\"left-nav-menu-track\">\n\t\t<div id=\"left-nav-wrapper\">\n\t\t\t<div class=\"rfi-above-anchor-tags\">\n\t\t\t\t<div class=\"ri-container\">\n\t\t\t\t\t<a href=\"https:\/\/nau.edu\/admissions\/request-information\/\" id=\"request-info\" class=\"btn bg-true-blue left-nav-menu-bottom-button display-mobile\">Request info&nbsp;&nbsp;<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div id=\"left-nav-menu\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"menu-section backcolor\">\n\t\t\t\t\t<div class=\"header\">\n\t\t\t\t\t\tHOW CAN WE HELP?\t\t\t\t\t<\/div>\n\t\t\t\t\t<ul class=\"responsive-icons\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li><a href=\"tel:928-523-4620\"><img decoding=\"async\" src=\"https:\/\/in.nau.edu\/wp-content\/themes\/nau-marketing-2021\/img\/icon-phone.svg\" alt=\"Telephone:\"> 928-523-4620<\/a>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t\t<li><a href=\"mailto:nauinnovations@nau.edu\"><img decoding=\"async\" src=\"https:\/\/in.nau.edu\/wp-content\/themes\/nau-marketing-2021\/img\/icon-email.svg\" alt=\"Email:\"><span class=\"left-nav-email\"> nauinnovations&#8203;@nau.edu <\/span><\/a><\/li>\n\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<section class=\"nau-block left-nav-section\"><header class=\"entry-header\"><div class=\"breadcrumb\"><ol class=\"breadcrumbs\"><li><a href=\"https:\/\/in.nau.edu\">IN<\/a><span class=\"breadcrumb-chevron\" aria-hidden=\"true\">&gt;<\/span><\/li><li><a href=\"https:\/\/in.nau.edu\/research\">Research<\/a><span class=\"breadcrumb-chevron\" aria-hidden=\"true\">&gt;<\/span><\/li><li class=\"current\">Pages<\/li><\/ol><\/div><h1 class=\"entry-title text-left \">Systems and Methods of Diagnosing and Characterizing Infections<\/h1><hr class=\"h1-hr  text-left \" role=\"none\"><\/header><!-- .entry-header --><\/section><!-- <section class=\"nau-block left-nav-section grid-md-12\">\n    <header class=\"entry-header\">\n        <h1 class=\"entry-title text-left \" tabindex=\"0\" id=\"h1-first\">Dummy H1<\/h1>\n        <hr class=\"h1-hr  text-left \" role=\"none\">\n    <\/header>\n<\/section> -->\n\n<section class=\"nau-block left-nav-section grid-md-12\">\n    <div class=\"page-content\">\n        \n\n<h2 class=\"wp-block-heading\">Description<\/h2>\n\n\n\n<p>The invention includes systems and methods to identify the presence of infectious microorganisms. Using nucleic acid sequencing, the technology assists with the diagnosis of infections and determines the presence of antimicrobial-resistance markers. One or more microorganisms can also be detected and characterized. Oligonucleotides are designed to provide multiplexed amplification of one or more markers, producing the desired amplicons. Following the production of amplicons, which may include the universal tail sequences, they are prepared for downstream sequencing. After processing and analysis of the sequencing data, a determination can be made about the microorganism\u2019s identity.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Additional information<\/h2>\n\n\n\n<section  \n    class=\"nau-block nau-block-panels   \" \n    data-layout_mobile=\"groupLayout-Stack gutter_Default panelLayoutPhotoTextVertical  photoAspect-1-1\"\n        data-layout_tablet=\"groupLayout-Stack gutter_Default panelLayoutPhotoTextVertical  photoAspect-1-1\"\n        data-layout_desktop=\"groupLayout-Tabs gutter_Default panelLayoutPhotoTextVertical  photoAspect-1-1\"\n        data-layout_xl=\"groupLayout-Tabs gutter_Default panelLayoutPhotoTextVertical  photoAspect-1-1\">\n\n    <div class=\"background-wrapper\">\n        <div class=\"block-main-content\">\n            \n            \n                            <div class=\"tab-nav\" role=\"tablist\" aria-label=\"Tabs for  articles\">\n                                                \n                        <button data-panel=\"panel--0\"\n                            role=\"tab\"\n                            aria-controls=\"panel--0\"\n                            class=\"active bg-true-blue bg-none\"\n                            tabindex=\"0\">Patent number and inventor<\/button>\n                                                \n                        <button data-panel=\"panel--1\"\n                            role=\"tab\"\n                            aria-controls=\"panel--1\"\n                            class=\"after-active bg-true-blue bg-none\"\n                            tabindex=\"-1\">Potential applications<\/button>\n                                                \n                        <button data-panel=\"panel--2\"\n                            role=\"tab\"\n                            aria-controls=\"panel--2\"\n                            class=\" bg-true-blue bg-none\"\n                            tabindex=\"-1\">Benefits and advantages<\/button>\n                                                \n                        <button data-panel=\"panel--3\"\n                            role=\"tab\"\n                            aria-controls=\"panel--3\"\n                            class=\" bg-true-blue bg-none\"\n                            tabindex=\"-1\">Case number and licensing status<\/button>\n                                    <\/div>\n            \n            \n            \n            <div class=\"panel-wrapper\">\n                \n                                \n                        <div class=\"panel bg-true-blue  panelTypeText  noHover \"\n                            data-role=\"tabpanel\"\n                            data-panel=\"panel--0\"\n                            id=\"panel--0\">\n\n                            \n                                                                    <div class=\"content\">\n                                            <div class=\"text-wrapper\">\n                                                                                                <h3 class=\"h3-tab-index\">Patent number and inventor<\/h3>\n                                                \n                                                                                                    <div class=\"text\">\n                                                        <p>15\/773,270<\/p>\n<p>Elizabeth Driebe, Jolene Bowers, David Engelthaler, and Paul Keim.<\/p>\n                                                    <\/div>\n                                                \n                                                                                            <\/div>\n                                        <\/div>\n\n                                    \n                                \n                                                        <\/div>\n                    \n                        <div class=\"panel bg-true-blue  panelTypeText  noHover \"\n                            data-role=\"tabpanel\"\n                            data-panel=\"panel--1\"\n                            id=\"panel--1\">\n\n                            \n                                                                    <div class=\"content\">\n                                            <div class=\"text-wrapper\">\n                                                                                                <h3 class=\"h3-tab-index\">Potential applications<\/h3>\n                                                \n                                                                                                    <div class=\"text\">\n                                                        <p>Clinical applications for hospital-acquired infections.<\/p>\n                                                    <\/div>\n                                                \n                                                                                            <\/div>\n                                        <\/div>\n\n                                    \n                                \n                                                        <\/div>\n                    \n                        <div class=\"panel bg-true-blue  panelTypeText  noHover \"\n                            data-role=\"tabpanel\"\n                            data-panel=\"panel--2\"\n                            id=\"panel--2\">\n\n                            \n                                                                    <div class=\"content\">\n                                            <div class=\"text-wrapper\">\n                                                                                                <h3 class=\"h3-tab-index\">Benefits and advantages<\/h3>\n                                                \n                                                                                                    <div class=\"text\">\n                                                        <p>While bacterial culturing remains the gold standard for diagnosis and characterizing drug resistance, the standard culturing process is time-consuming and requires specific microbiological skills and facilities. This invention provides a novel approach, using a multiplex-targeted sequence analysis system for the detection and characterization of antimicrobial resistance markers in\u00a0Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter species, and\u00a0Staphylococcus aureus. The aim is to improve the detection and treatment of hospital-acquired infections.<\/p>\n                                                    <\/div>\n                                                \n                                                                                            <\/div>\n                                        <\/div>\n\n                                    \n                                \n                                                        <\/div>\n                    \n                        <div class=\"panel bg-true-blue  panelTypeText  noHover \"\n                            data-role=\"tabpanel\"\n                            data-panel=\"panel--3\"\n                            id=\"panel--3\">\n\n                            \n                                                                    <div class=\"content\">\n                                            <div class=\"text-wrapper\">\n                                                                                                <h3 class=\"h3-tab-index\">Case number and licensing status<\/h3>\n                                                \n                                                                                                    <div class=\"text\">\n                                                        <p>2016-001<\/p>\n<p>This invention is available for licensing.<\/p>\n                                                    <\/div>\n                                                \n                                                                                            <\/div>\n                                        <\/div>\n\n                                    \n                                \n                                                        <\/div>\n                                                <\/div>\n\n                    <\/div>\n    <\/div>\n<\/section>\n\n    <\/div>\n<\/section>\n\n<div class=\"nau-block nau-block-left-nav-bottom-bound\">\n\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":276,"featured_media":1037,"parent":65,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","ring_central_script_selection":"","footnotes":""},"class_list":["post-301","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/in.nau.edu\/research\/wp-json\/wp\/v2\/pages\/301","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/in.nau.edu\/research\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/in.nau.edu\/research\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/in.nau.edu\/research\/wp-json\/wp\/v2\/users\/276"}],"replies":[{"embeddable":true,"href":"https:\/\/in.nau.edu\/research\/wp-json\/wp\/v2\/comments?post=301"}],"version-history":[{"count":14,"href":"https:\/\/in.nau.edu\/research\/wp-json\/wp\/v2\/pages\/301\/revisions"}],"predecessor-version":[{"id":6103,"href":"https:\/\/in.nau.edu\/research\/wp-json\/wp\/v2\/pages\/301\/revisions\/6103"}],"up":[{"embeddable":true,"href":"https:\/\/in.nau.edu\/research\/wp-json\/wp\/v2\/pages\/65"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/in.nau.edu\/research\/wp-json\/wp\/v2\/media\/1037"}],"wp:attachment":[{"href":"https:\/\/in.nau.edu\/research\/wp-json\/wp\/v2\/media?parent=301"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}