{"id":72862,"date":"2024-09-05T12:16:38","date_gmt":"2024-09-05T19:16:38","guid":{"rendered":"https:\/\/in.nau.edu\/news\/?p=72862"},"modified":"2024-09-05T12:16:38","modified_gmt":"2024-09-05T19:16:38","slug":"berns-brain-aneurysms","status":"publish","type":"post","link":"https:\/\/in.nau.edu\/news\/berns-brain-aneurysms\/","title":{"rendered":"Using AI to prevent ruptured brain aneurysms\u00a0"},"content":{"rendered":"<p><span data-contrast=\"auto\">A Northern Arizona University doctoral student is being recognized by the Brain Aneurysm Foundation for her work using AI and machine learning to prevent hemorrhagic stroke and other potentially fatal effects of a ruptured aneurysm.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Bioengineering student <strong>Holly Berns<\/strong> is leading a project that looks at whether variations in the <\/span><a href=\"https:\/\/emedicine.medscape.com\/article\/1877617-overview?form=fpf\"><span data-contrast=\"none\">circle of Willis<\/span><\/a><span data-contrast=\"auto\">, a ring of arteries at the base of the brain, can contribute to early, proactive detection of brain aneurysms. Her goal is to learn if certain factors about these arteries contribute to aneurysm formation, which can indicate a person is higher risk, which, she hopes, means more proactive treatments and fewer ruptured aneurysms.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">\u201cThis research could advance the field of aneurysm detection and guide treatment for the nearly 6.7 million Americans who live with an unruptured cerebral aneurysm,\u201d Berns said.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-72863\" src=\"http:\/\/in.nau.edu\/news\/wordpresst\/uploads\/sites\/153\/wp-content\/uploads\/2024\/09\/image_123650291-644x1024.jpg\" alt=\"Holly Berns headshot\" width=\"241\" height=\"383\" srcset=\"https:\/\/in.nau.edu\/wp-content\/uploads\/sites\/402\/2024\/09\/image_123650291-644x1024.jpg 644w, https:\/\/in.nau.edu\/wp-content\/uploads\/sites\/402\/2024\/09\/image_123650291-189x300.jpg 189w, https:\/\/in.nau.edu\/wp-content\/uploads\/sites\/402\/2024\/09\/image_123650291-768x1220.jpg 768w, https:\/\/in.nau.edu\/wp-content\/uploads\/sites\/402\/2024\/09\/image_123650291-967x1536.jpg 967w, https:\/\/in.nau.edu\/wp-content\/uploads\/sites\/402\/2024\/09\/image_123650291.jpg 1110w\" sizes=\"auto, (max-width: 241px) 100vw, 241px\" \/>Her hypothesis is simple: A certain range of angles of the feeding arteries within the circle of Willis (CW) may be a predictor or cause of abnormally high hemodynamics at the artery transitions, which can eventually lead to the formation of aneurysms. In this study, she will use AI and machine learning algorithms to isolate the CW arteries from imaging of patients, calculate CW tilt angles and categorize CW tilt angles in male and female patients with and without existing aneurysms.\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">If her hypothesis is correct, it could play a role in changing how doctors treat aneurysms, including taking proactive steps to prevent rupture, which can have catastrophic events; according to the Brain Aneurysm Foundation, ruptured brain aneurysms are fatal about half the time, and even when a person survives, they often have significant and permanent brain injury. It also has a role in increasing health equity; women are 50% more likely to have a brain aneurysm than men, and Hispanics and Black people are twice as likely as white people to have an aneurysm rupture.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">\u201cWe are hoping to discover that CW tilt angles can be used to help in cerebral aneurysm detection,\u201d she said. \u201cIdentifying patients who are at-risk would allow for proactive screening and follow-ups, as well as informed treatment method to reduce the prevalence of subarachnoid hemorrhage from aneurysm rupture, drastically reducing patient morbidity and mortality as well as reducing hospitalizations and overall healthcare costs.\u201d<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/in.nau.edu\/news\/becker-stroke-research\/\"><span data-contrast=\"none\">Read more about Berns\u2019 research into ischemic strokes and her efforts to create a stroke treatment catheter that better fits women\u2019s bodies.<\/span><\/a><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-ccp-props=\"{}\">\u00a0<\/span><span data-contrast=\"auto\">Berns will be recognized at the BAF\u2019s 18th Annual Research Grant Symposium, which will be held in Boston on Sept. 12. She and fellow Ph.D. student <strong>Steve Schwartz<\/strong> will conduct the work in the coming year.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-56007\" src=\"http:\/\/in.nau.edu\/news\/wordpresst\/uploads\/sites\/153\/wp-content\/uploads\/2019\/06\/NAU_primary-281_3514-300x213.png\" alt=\"Northern Arizona University Logo\" width=\"117\" height=\"83\" srcset=\"https:\/\/in.nau.edu\/wp-content\/uploads\/sites\/402\/2019\/06\/NAU_primary-281_3514-300x213.png 300w, https:\/\/in.nau.edu\/wp-content\/uploads\/sites\/402\/2019\/06\/NAU_primary-281_3514-768x546.png 768w, https:\/\/in.nau.edu\/wp-content\/uploads\/sites\/402\/2019\/06\/NAU_primary-281_3514-600x426.png 600w, https:\/\/in.nau.edu\/wp-content\/uploads\/sites\/402\/2019\/06\/NAU_primary-281_3514.png 905w\" sizes=\"auto, (max-width: 117px) 100vw, 117px\" \/><\/p>\n<p>Heidi Toth | NAU Communications<br \/>\n(928) 523-8737<\/p>\n<p><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p><a class=\"search-results-excerpt-link\" href=\"https:\/\/in.nau.edu\/news\/berns-brain-aneurysms\/\">A Northern Arizona University doctoral student is being recognized by the Brain Aneurysm Foundation for her work using AI and machine learning to prevent hemorrhagic stroke and other potentially fatal effects of a ruptured aneurysm.\u00a0 Bioengineering student Holly Berns is leading a project that looks at whether variations in the circle of Willis, a ring&hellip;<\/a><\/p>\n","protected":false},"author":59,"featured_media":72864,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[11],"tags":[],"class_list":["post-72862","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-academics"],"acf":[],"_links":{"self":[{"href":"https:\/\/in.nau.edu\/news\/wp-json\/wp\/v2\/posts\/72862","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/in.nau.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/in.nau.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/in.nau.edu\/news\/wp-json\/wp\/v2\/users\/59"}],"replies":[{"embeddable":true,"href":"https:\/\/in.nau.edu\/news\/wp-json\/wp\/v2\/comments?post=72862"}],"version-history":[{"count":0,"href":"https:\/\/in.nau.edu\/news\/wp-json\/wp\/v2\/posts\/72862\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/in.nau.edu\/news\/wp-json\/wp\/v2\/media\/72864"}],"wp:attachment":[{"href":"https:\/\/in.nau.edu\/news\/wp-json\/wp\/v2\/media?parent=72862"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/in.nau.edu\/news\/wp-json\/wp\/v2\/categories?post=72862"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/in.nau.edu\/news\/wp-json\/wp\/v2\/tags?post=72862"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}